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In normal endothelial cells, nitric oxide is synthesized and released to maintain vascular homeostasis

Notably, the reduction of lipid peroxidation with ergothioneine supplementation has been reported in multiple injury models (Reference Dare, Channa and Nadar67,Reference Bedirli, Sakrak and Muhtaroglu84,Reference Sakrak, Kerem and Bedirli85,Reference Dare, Channa and Nadar91) and is of relevance to non-alcoholic fatty liver disease (NAFLD) pathogenesis

Finally, we discuss the potential of current therapeutic approaches, including antibiotics, probiotics, prebiotics, and fecal microbiota transplantation, in modulating the gut microbiota, affecting ferroptosis, and improving IBD symptoms

[DOI] [PubMed] [Google Scholar] 81.Tayab M.A., Islam M.N., Chowdhury K.A.A., Tasnim F.M