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As a border collie mix, Yuki may also have been a carrier for intestinal cobalamin (B12) malabsorption, the genetic mutation originally found in border collies

Loss of VadK causes methylcitrate cycle hyperflux, disrupting central carbon metabolism, redox balance and bioenergetics

Nevertheless, this latter in vivo study demonstrates that homocysteine ingestion in rat stimulates, in a dose-dependent manner, the transcription of aortic cyclin-dependent kinase, which is required for the mitosis and subsequent proliferation of vascular smooth muscle cells

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