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Nicotine is the main harmful substance in cigarettes, and nicotine affects male reproductive function by disrupting blood-testis barrier dynamics [108]
The involvement of the IGF system as intraovarian regulators of folliculogenesis has been intensively studied in a variety of mammal species, and it is now established that the ovary is a site of IGF-I gene expression and reception[102]
Podlipna, D
[DOI] [PMC free article] [PubMed] [Google Scholar] 27.Harris I.S., Treloar A.E., Inoue S., Sasaki M., Gorrini C., Lee K.C., Yung K.Y., Brenner D., Knobbe-Thomsen C.B., Cox M.A., et al
