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Description
it competitively binds to cellular receptors, blocking the body's natural active B6 and potentially inducing a functional deficiency that leads to peripheral neuropathy (nerve tingling and pain)
64 NBDHEX and its analogs NBDHEX (6-[7-nitro-2,1,3-benzoxadiazol-4-ylthio]hexanol) is a recently developed compound designed as a mechanism-based inhibitor that exerts potent effects on GST
2021;67 doi: 10.1016/j.arr.2021.101271
these effects were similarly accompanied by an increase in inactivated GSK-3 expression and -catenin activity
