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It is important to mention that after AMPK activation, it subsequently activated SIRT-1 and hampered m-TOR, an autophagic suppressor, thus enhancing autophagy, with promoting the expression of an autophagy-related marker, beclin-1 and endorsing neuronal survival (ElLatif et al

doi: 10.21470/1678-9741-2018-0287

However, CBD- and THC oils would help in these observed changes
