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Immunometabolism is an emerging research field in which immune cells regulate energy and biosynthesis through pathways such as glycolysis, oxidative phosphorylation, and tricarboxylic acid cycle in different microenvironments to meet proliferation, differentiation, and effector functions (18)

The important representatives of this group include acetyl-L-carnitine, which is a source of acetylcholine precursors, acetyl, choline, lecithin, and pyrrolidine derivatives [156,157]

TMA is typically produced during the digestion of choline- and carnitine-rich foods, and it is normally metabolized by the liver enzyme flavin-containing monooxygenase 3 (FMO3) (Fig

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