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A study published in 2018 established baseline GSH levels, and found that those with low GSH status at baseline also had lower physical performance, increased oxidative stress and impaired redox metabolism of erythrocytes at baseline compared with those with medium or high levels

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The other NAD forms showed only modest increases in response to niacin, suggesting differential regulation of individual metabolite pools in steady state

Although it is a thiol, and hence an antioxidant (32,33) , the thione tautomer is predominant at physiological pH (34,35) , and this makes it unusually resistant to autoxidation, i.e