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J Oral Biol Craniofac Res

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The TXN2 gene encodes thioredoxin-2, that reduces Prx dimers that are formed upon reaction with H 2 O 2 , thereby keeping Prx in their reduced and active state (Supplementary Figure S3)
This, in turn, leads to reduced m, MPTP opening, proapoptotic factor release, increased ROS production, and decreased ATP production (Fig
