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One 2013 study found that patients with Hashimotos had 62 percent lower levels of serum glutathione compared to the control group
[DOI] [PMC free article] [PubMed] [Google Scholar] 105.Saxe-Custack A, Lachance J, Hanna-Attisha M
Based on domain architecture comparison with HNF4 58,59 , we engineered an NHR-49 truncation (295422) to disrupt ligand binding by removing a majority of the ligand binding domain, while retaining its analogous N-terminal, DNA-binding, hinge, and C-terminal domains (Fig
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