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In PTSD mice models, trauma exposure increased tyrosine hydroxylase expression (the rate-limiting enzyme in catecholamine biosynthesis), elevating stress hormones epinephrine and norepinephrine in serum and colon, which upregulated claudin-2 expression, confirming gut barrier dysfunction (Yadav et al., 2023)
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[DOI] [PubMed] [Google Scholar] 95.Singh N., Saha L., Kumari P., Singh J., Bhatia A., Banerjee D., Chakrabarti A
