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Yao Y, Chinnici C, Tang H, Trojanowski JQ, Lee VM, Pratic D

The pharmacological effects observed on the CNS in experimental models associated with a specific stress level suggest that pomegranates could simultaneously modulate the stress response by activating several targets

4 Conclusion and perspectives Application of antioxidants, pharmacologic activators of endogenous antioxidant systems, selective serotonin reuptake inhibitors, and MAO inhibitors may serve to decrease the deleterious effects of ROS in the pathogenesis of PTSD

Second, experimental standardization remains challenging, given the variability among xenografts generated from different patients