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Thesignsandsymptomsof thedeficiencymay include anemia , the buildup of too much acid in the body (metabolic acidosis), frequent infections, andsymptomscaused by problems in the brain including seizures , intellectual disability , and loss of coordination ( ataxia )

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Glutathione synthetase deficiency is a rare autosomal recessive disorder resulting in low levels of glutathione and an increased susceptibility to oxidative stress