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3.1 Physical protection The first study aimed at producing protected AA occurred in the 1960s when most research focused on developing methods to protect Met from ruminal degradation (Mazinani et al., 2022)

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These results collectively indicate that Sirt1 is indispensable for NNMT-mediated regulation of glucose metabolism, and both NNMT and MNAM have the ability to upregulate Sirt1 expression