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Enlarged spleen: thalassemia can cause the spleen to enlarge as it tries to filter out abnormal red blood cells
127 RamakrishnanV.XuB.AkersJ.NguyenT.MaJ.DhawanS.et al (2020)
Which is part of why a peptide first pulled out of human plasma back in 1973 still keeps turning up in anti-aging conversations five decades later
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