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doi: 10.1038/onc.2016.502

In their studies, structural modifications were made to replace the piperazine sulfonamide part of sildenafil and vardenafil with groups that have a terminal zinc binding group ZBG (a hydroxamic acid or an ortho-aminoanilide moiety), which is essential for HDAC inhibition

Diosmin mitigates gentamicin-induced nephrotoxicity in rats: Insights on miR-21 and-155 expression, Nrf2/HO-1 and p38-MAPK/NF-B pathways

The motor scale part III of the United Parkinson's Disease Rating Scale (mUPDRS III), Korean mini mental state examination (KMMSE), clinical dementia rating (CDR), and magnetic resonance imaging (MRI) with diffusion weighted image (DWI) were performed