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These metabolic features of NRF2 addiction status provide clues for novel therapeutic strategies to target NRF2-addicted cancer cells.
Cats and dogs possess a combined repertoire of at least 27 cytosolic glutathione transferases belonging to the GST-A, -M, -P, -T, -Z and -O classes, with the greatest genetic diversity observed for the GSTA, GSTM, GSTP, and GSTT classes
