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Deprivation of external L-serine through genetic depletion of L-serine biosynthetic enzyme leads to the generation of DSBs, including DoSa in mouse embryonic fibroblasts, which can be further suppressed or potentiated by supplementing exogeneous L-serine or increasing the ratio of L-serine to L-alanine, respectively [65]
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J Endocrinol 257(1):e220271
