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Administered either alone or with other bronchodilators, especially beta adrenergics

213 Thus, -ketoglutarate as a co-factor for histone demethylases likely has many target genes whose regulation may be sensitive to different concentrations of -ketoglutarate and other cellular contexts

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p16 INK4a is widely recognized as a biomarker of cellular senescence (Omori et al., 2020)
