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While sodium's significance in the context of epilepsy is evident, the specific mechanisms through which alterations in sodium channels or sodium levels contribute to epileptogenesis may differ based on the subtype or cause of epilepsy[147]

In line with these findings, iberdomide at a 0.45 mg oral daily dose significantly increased the percentage of patients achieving an SRI-4 response at week 24 compared to the placebo group, especially in subjects with a high Aiolos or type 1 interferon gene expression signature in a phase 2 clinical study (84)

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Stable loss of global DNA methylation in the radiation-target tissue-A possible mechanism contributing to radiation carcinogenesis
