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2003 Dec;90(6):1081-5

doi: 10.1016/j.ab.2006.05.032

The role of triterpenes in the management of diabetes mellitus and its complications

Dihydroartemisinin (DHA) exemplifies this duality: at low concentrations or under specific conditions, DHA can paradoxically increase GPX4 activity by upregulating ATF4 expression, potentially suppressing ferroptosis
