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A double-blind, randomized, placebo-controlled crossover study of memantine monotherapy (60 patients, 43 completed) found no significant improvement in Tinnitus Handicap Inventory scores compared with placebo, leading the authors to conclude that the study does not provide evidence to recommend memantine for tinnitus treatment (Figueiredo et al., 2008)

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For dosing in your experiments, a U-100 insulin syringe (typically 1 mL, 0.5 mL, or 0.3 mL) is the standard choice due to its fine, easy-to-read unit markings

We thank the Cornell University Biotechnology Resource Center for performing the sequencing