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Description
Study participants with Parkinsons disease, who had intramuscular injections of thiamine twice per week, experienced a 49% improvement in overall function and a 55.5% decrease in fatigue

B complex vitamins may cause a boost in energy and cause sleep disruptions

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This effect has been previously demonstrated in an infant rat model of pneumococcal meningitis 17 and in whole blood cultures from human patients with acute COVID-19 18
