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Description
To exclude the possibility that increased apoptosis contributed to the reduction in SC- cells, we performed terminal deoxynucleotidyl transferase biotin-dUTP nick end labeling (TUNEL) staining to evaluate apoptosis in SC- cells
The efficacy of TMZ is intricately linked to the proper functioning of the MMR system, which explains why the downregulation of MLH1 can result in resistance to TMZ [161]
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It helps researchers understand mitochondrial-nuclear communication and metabolic adaptation
