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The upregulated CD38 was also observed during the aging process, by secreted cytokines IL-6, interferons and soluble factors from senescent cells as part of so-called senescence-associated secretory phenotype (SASP) 21,27,36,47,48,49,50
Faster collagen synthesis means structural repair that would otherwise take months begins within days of starting the protocol

Seiwerth et al., Frontiers in Pharmacology (2021) and Xing et al., Int J Mol Sci (2021)
