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Therefore, the acidic residues of p53 TAD appear to have no significant impact on its interaction with the FOXO4 FHD, as these residues primarily contribute to DNA selectivity rather than binding to the FOXO4 FHD
Whitney ER, Kemper TL, Bauman ML, Rosene DL, Blatt GJ

52,340 The NAD + decline is a primary driver for the progressive of biological dysfunction and age-related pathologies

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