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National Health and Nutrition Examination Survey (NHANES) indicates that approximately 21% of adults, or 43 million individuals, have been diagnosed with hyperuricemia

CDX2 is also inhibited by SMYD2 -mediated MEX3A to enhance CRC progression (Pan et al., 2022), Decreased expression of CDX2 is more dependent on the CpG island hypermethylation phenotype (CIMP-H) (Lee et al., 2022)

Thus, further research is warranted to mitigate these inconsistencies to make robust conclusions on how APOE4 influences DLB-related cognitive impairment via increasing amyloid-beta proteins also

Consistency is key results build up over time