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The imbalance between oxygen supply and demand Reduced energy stores Complexity of treatment Lack of recall Lack of resources New condition or treatment Unfamiliarity with the disease condition Bone marrow malfunction Marrow replacement with fat in aplastic anemia Inflammatory response Vaso-occlusive nature of sickling (sickle cell anemia) Decreased hemoglobin and hematocrit levels Nursing Diagnosis Following a thorough assessment, a nursing diagnosis is formulated to specifically address the challenges associated with anemia based on the nurses clinical judgement and understanding of the patients unique health condition