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While balanced lethal systems, such as asd gene complementation, are widely employed to maintain plasmid stability at a high rate of exceeding 95%, they do not completely impede evolutionary escape. In this process, bacteria acquire mutations that shut down the expression of metabolically costly or toxic proteins to restore their fitness

Each BPC-157 batch undergoes rigorous purity verification procedures before distribution

Kong AT, Leprevost FV, Avtonomov DM, Mellacheruvu D, Nesvizhskii AI

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