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Nutrient interactions Biotin The chemical structure of biotin is similar to that of lipoic acid, and there is some evidence that high concentrations of lipoic acid can compete with biotin for transport across cell membranes (120, 121)

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Adiponectin inhibits insulin function in primary trophoblasts by PPAR-mediated ceramide synthesis

To further identify the bridge between IGF1R pathways and ASS1/PYCR1, multiple transcription factors (TFs) have attracted our attention, which play a crucial role in regulating cancer metabolism during hypoxia [27, 28], and there transcriptional activity could be enhanced due to phosphorylation by RTK pathways [29]