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When you have pernicious anaemia, the body attacks your healthy cells which makes it impossible for your body to absorb vitamin B12
So if we say that the, the modernist society is polluted, the answer is absolutely yes

[DOI] [PMC free article] [PubMed] [Google Scholar] 55.Cluntun A.A., Lukey M.J., Cerione R.A., Locasale J.W

Vitamin B12 Shots vs B12 Supplements When it comes to boosting your Vitamin B12 levels, both supplements and shots can be effective, but there are some differences to consider
