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[28] found that NNMT knockdown significantly reduced the body weight, fat mass, and insulin level of female mice fed a Western diet (fat 47% kcal, carbohydrate 34% kcal), as did NNMT knockout

Cancer Res 2009;69: 302131
For example, ITC-rich extracts of Moringa oleifera leaf (500 mg/kg administered 30 min prior to tests) induced anxiolytic effects in Swiss mice in lightdark and open field tests (OFT) (137)

This metabolic shift shows promise in cancer management by targeting malignant cells while preserving healthy tissue function
