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Keavney B, McKenzie C, Parish S, Palmer A, Clark S, Youngman L et al
The beneficial effects of exercise on general health, immune responses, metabolic syndrome and central nervous system in infection, old age, neurodegenerative diseases and cancer are well-documented (Nieman and Sakaguchi, 2022)
CBS deficiency led to markedly homocysteine accumulation and severely decreased levels of cystathionine and cysteine, which was due to impaired homocysteine removal through the transsulfuration pathway [32]
This oxidative stress triggers lipid peroxidation, the hallmark of ferroptosis
