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In principal cells derived from rodent hippocampus, an acute elevation in O-GlcNAcylation was observed to attenuate GABAergic currents and reduce synaptic spikes through synaptic depression and reduced intrinsic excitability [70]

Synergistic effects of telomerase reverse transcriptase and regulator of telomere elongation helicase 1 on aggressiveness and outcomes in adrenocortical carcinoma

The phosphatidylinositol 3-kinase (PI3K)/AKT and Janus kinase (JAK)/signal transducer and activator of transcription 3 (STAT3) signaling pathways were hindered, and the p38-MAPK pathway was promoted under these conditions, resulting in G1 phase arrest and autophagy in the osteoblast cell line MC3T3-E1 (Cen et al., 2018)

They did not observe an increased proliferation of melanoma cells upon NAC implementation