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4 integrates extracellular stress and growth cues to regulate cell-cycle progression, apoptosis, and differentiation, and frequently cooperates with NF-B signaling to promote cancer cell survival and metastasis

The NOAEL for these effects was 25 mg/kg/day

Org Lett 2021, 23 (22), 87898793

1 Introduction Glucose homeostasis in the circulatory system, which is vital for meeting the energy demands of organisms, is regulated by hormones, and relies on the balance between glucose uptake, synthesis, and oxidation ( In humans, PPP has been recognized as a crucial pathway strongly associated with several important pathologies
