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15,16 On the basis of these strategies, functional materials with small size, tailored architecture and therapeutic motifs that facilitate the targeted drug delivery are widely engineered

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In the systemic circulation, metal-based NPs could absorb a variety of proteins like albumin, immunoglobin, and other functional biomolecules to the surface of metal-based NPs to form a protein corona, which has been reported to alter the surface properties of metal-based NPs (Duran et al., 2015

Brain 138 , 18631874 (2015)
