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Omaveloxolone was therefore specifically synthesized and pharmacologically optimized to eliminate this fluid-retaining liability while maintaining target selectivity, making it suited for the highly vulnerable cardiac and neurological landscape of FRDA [108,112]
Duan Q, Kita D, Johnson EA, Aggarwal M, Gates L, Wu HM, et al
Biophysical investigation of the ironome of human jurkat cells and mitochondria
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