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Chronic administration of EGCg was shown to support the reduction of behavioral deficits, significantly decreasing immobility time, post-exertional fatigue, and pain sensitivity (hyperalgesia)
In addition, individuals who took L-dopa exhibited improved performance compared with the control group
Studies have postulated that the cause may be ascribed to the reduction in the excitability of pain transmitting dorsal horn neurons via hyperpolarization due to MT1/2-melatonin binding 89
Glutathione synthetase deficiency is transmitted as an autosomal recessive condition
