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Description
An imbalance in eicosanoid production, such as increased pro-inflammatory leukotrienes and decreased anti-inflammatory prostaglandins levels, has been implicated in ARDS pathogenesis
Noteworthy, all these factors act by promoting an increase in oxidative stress via mitochondrial defects and the production of ROS and RNS [132]
Ethics statement The animal study was reviewed and approved by Ethics Committee of Nanjing Medical University
Curr Mol Pharmacol 14: 220233, 2020
