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The wrong one can leave the dose in the wrong place or make the whole thing hurt more than it should

Finally, a four-year, multicenter, clinical trial in 421 diabetic patients with distal symmetric sensorimotor polyneuropathy found no difference between oral administration of 600 mg/day of lipoic and placebo on the primary endpoint, a composite score that assessed neuropathic impairment of the lower limbs and nerve conduction (78)

doi: 10.1002/brb3.558

Alternatively, the amino acids can be degraded to provide carbon skeletons as an energy source or for the synthesis of glucose