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Finally, increases in reactive oxygen species (ROS) and ER stress also occur in target tissues in states of insulin resistance, leading to activation of JNK, IKK isoforms and other Ser/Thr kinases [81, 82]

Eat foods rich in sulfur and antioxidants like: Spinach Avocado Broccoli Garlic Nuts Seeds Alongside: Exercise regularly Reduce stress Sleep right Hydrate well Avoid smoking and pollution exposure when possible These habits improve glutathione levels naturally and safely

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9a), the highly reactive hydroxyl radical is a potent source of damage to biomolecules, attacking, for example, the double bond in fatty acids in the membranes to form peroxides