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this reduces the enzymatic activity of MTHFR by approximately 35% per T allele , resulting in inefficient production of methylfolate ( Figures 3 and 4)
Nrf2, nuclear factor erythroid 2related factor 2
Thus, the lipid-modifying actions of niacin, where niacin promotes cholesterol efflux and regulates CNS cholesterol and lipid homeostasis (Fig
New findings validate the site-and cell-specific character of MeHg-induced neurotoxicity, as well as the role of oxidative stress in its pathophysiology [66]
