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(II) the subsequent protonation to form *OOH on the top of Fe atoms

History of Milk Thistle Pliny the Elder referred to medicinal plants of his time in his work Naturalis Historia

While there is no clear explanation of vitamin C's effect on levothyroxine malabsorption, there has been a suggestion that high gastric pH may interfere with levothyroxine absorption, and therefore, decreasing pH via vitamin C can enhance the drug's absorption