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Currently available guidelines for the treatment of hypertension should be followed

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6 This article focuses on recent changes in the definition and diagnosis of PH, highlighting diagnostic and management strategies appropriate for the Australian setting and emphasising developments in the identification and treatment of two types of PH: PAH, for which there is now access to combination therapy, and chronic thromboembolic pulmonary hypertension (CTEPH)

Temozolomide (TMZ), the standard first-line chemotherapeutic agent for glioma, encounters therapeutic resistance in approximately 60% of patients