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Description
This review integrates current evidence on how brain peptides contribute to AD pathophysiology, summarizes recent progress in peptide-based therapeutic strategies and delivery platforms, and critically examines the remaining barriers to clinical translation, including bloodbrain barrier penetration, metabolic stability, off-target effects, and the need for biomarker-guided patient stratification

This is different from oral vitamin supplements, which are taken by mouth and must be digested and absorbed through the digestive system.

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They can also decrease due to toxin exposure, stress, heavy metals and alcohol consumption, therefore supplementation may be beneficial
