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Drug Insight: prolactin-receptor antagonists, a novel approach to treatment of unresolved systemic and local hyperprolactinemia

HGF, the ligand of c-MET, is secreted as a single chain 83 kDa precursor protein containing an N-terminal (N) domain, four consecutive kringle (K1K4) domains, and a serine protease homology (SPH) domain (Fig

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Van Cauter, E
