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In addition to its well-known catalytic activity in intracellular glutathione conjugation and metabolism, GSTM1 acts through its non-catalytic domain to inhibit activation of the ASK1-p38 signaling pathway of apoptosis

Biopolymers 2010

The safety and tolerability of oral AZD5069, a selective CXCR2 antagonist, in patients with moderate-to-severe COPD

thus, the timely diagnosis and treatment of such diseases can prevent further complications
