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Additional efficacy outcome measures were ORR and duration of response, as assessed by the BICR according to RECIST v1.1, modified to follow a maximum of 10 target lesions and a maximum of 5 target lesions per organ

Torsvik I, Ueland PM, Markestad T, et al
The body tightly regulates vitamin levels, and excess water-soluble vitamins like B12 are typically excreted in urine