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Lipid droplets have received a lot of attention the past few years and have been consistently progressing from being considered a simple fat reserve towards being recognized as an important intervenient in a variety of cellular functions and having a close relationship with many organelles such as the endoplasmic reticulum (ER), mitochondria, peroxisomes and vacuoles (Beller et al

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[24] Therefore, PIP 2 depletion by the PLC reaction is critical to the regulation of local PIP 3 concentrations both in the plasma membrane and the nuclear membrane

Nowak R, Oelschlaegel U, Schuler U, Zengler H, Hofmann R, Ehninger G, Andreeff M