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Furthermore, microRNA sequence analysis showed that IMSC-SEVs were highly enriched in miR-105-5p, which had a pivotal role in the IMSC-SEV-mediated therapeutic effect by downregulating the level of cAMP-specific hydrolase PDE4D and leading to SIRT6 activation [95] (Table 7)

doi: 10.1021/acssynbio.4c00589 84 XiaJZhangLZhuWTuJPengXDengQet al

Click below to know more: Combination of topical and oral glutathione as a skin-whitening agent: a double-blind randomized controlled clinical trial
