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For ABPP analyses only, outlier samples (based on low precursor identifications or clustering by principle coordinate analysis) were removed, leaving a minimum of 3/4 samples per condition

The role of GSH metabolism in cell differentiation, proliferation and apoptosis has been previously shown to lead to cancer progression and chemoresistance 21

doi: 10.1002/jnr.20025

Since constipation may exacerbate hemorrhoids, prevention and treatment of constipation is also recommended
